Findings that shed new light on the possible pathogenesis of a disease or an adverse effect
Mild clinical expression of Lambert–Eaton myasthenic syndrome in a patient with HIV infection
University Hospital of Geneva, Micheli-du-Crest 24, Geneva 14, 1211, Switzerland
Correspondence to:
patrice.lalive{at}hcuge.ch
Neuromuscular complications of HIV are related to immunodeficiency, direct cytotoxicity of the virus or side effect of the treatments. Autoimmune disorders involving the nervous system, including Guillain–Barre syndrome, myositis and vasculitis, have been described in association with HIV. Neuromuscular junction autoimmune diseases such as myasthenia gravis have been occasionally reported in patients with HIV, whereas the Lambert–Eaton myasthenic syndrome (LEMS) has never been described. We report an unusual case of paucisymptomatic LEMS in a patient with HIV infection.
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