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Published 26 February 2009
Cite this as: BMJ Case Reports 2009 [doi:10.1136/bcr.06.2008.0334]
Copyright © 2009 by the BMJ Publishing Group Ltd.

Unexpected outcome (positive or negative) including adverse drug reactions

Oxaliplatin-induced coronary artery spasm: first report of an important side-effect

Jens Samol1, Ashita Waterston2

1 Beatson Oncology Centre, Medical Oncology, Gartnavel General Hospital, 1053 Great Western Road, Glasgow G12 0YN, UK
2 Beatson Oncology Centre, Medical Oncology, West of Scotland Cancer Centre, 1053 Great Western Road, Glasgow G12 0YN, UK

Correspondence to:
jens.samol{at}gmail.com

SUMMARY

A 67-year-old woman with metastatic colorectal cancer was given her first oxaliplatin infusion as part of the XELOX protocol. She developed chest pain with ECG changes leading subsequently to a diagnosis of coronary artery spasm. To our knowledge, this is the first report of oxaliplatin-induced coronary artery spasm.


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