Unusual presentation of more common disease/injury
Extensively drug resistant tuberculosis in a 7-year-old child with interferon-
and interleukin-12 deficiency
Department of Pediatrics, Advanced Pediatrics Center, PGIMER, Chandigarh, 160012, India
Correspondence to:
meenusingh4{at}rediffmail.com
Defects in interferon-
axis have been shown to be associated with disseminated mycobacterial disease. A case of a previously healthy HIV seronegative child with disseminated extensively drug resistant Mycobacterium tuberculosis infection presenting as splenic abscesses with lymphadenopathy and progressing to disseminated tuberculosis with absent interferon- and interleukin-12 production is reported here.
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