http://casereports.bmj.com This feed contains articles for BMJ Case Reports Subject Collection "Smoking and tobacco" BMJ Case Reports http://casereports.bmj.com http://casereports.bmj.com/cgi/content/short/2011/sep13_1/bcr0820114621?rss=1 Buerger's disease or Thromboangiitis obliterans is a segmental inflammatory disease that affects the vessels and nerves of the extremities. It usually affects men below 45 years old and correlates with tobacco, as a predisposing factor. The authors present the case of a 34-year-old male, with ulcers in the fingertips with progressive worsening: acrocyanosis, slow healing, necrosis and finally loss of substance. Dorsalis pedis and posterior tibial pulses were not palpable. Personal history of heavy smoking was (20 pack-years). The angiography revealed proximal occlusion of the left posterior tibial and interosseal arteries, with distal circulation by the anterior tibial artery. He was submitted to disarticulation of the second left toe and therapy with pentoxifyline and iloprost infusion, calcium antagonist, antiplatelet drugs, statin and low molecular weight heparin (later replaced by oral anticoagulation). Improvement was seen of active vascular lesions and pain symptoms. Jorge, V. C. Araujo, A. C. Noronha, C. Panarra, A. Riso, N. Vaz Riscado, M. 2011-09-13 doi:10.1136/bcr.08.2011.4621 Buerger's disease (Thromboangiitis obliterans): a diagnostic challenge BMJ Publishing Group Ltd SEP13_1 2011 82011462 2011-09-13 CASE-REPORT http://casereports.bmj.com/cgi/content/short/2010/nov26_1/bcr0820103252?rss=1 Primary adenoid cystic carcinoma (ACC) of the lung is an extremely rare malignant lung neoplasm. ACC of salivary glands of the head and neck, lachrymal glands, breast, skin, vulva and trachea have been frequently reported disease patterns in the literature, but it is unique to see this rare lung tumour in a patient as young as 14 years old. No double blind placebo, multicentre treatment data are available. Surgery is considered as the cornerstone of the treatment. Prognosis is variable and adjuvant radiotherapy has been found beneficial for prolonged survival. Our report of primary lung ACC in a young girl is a complex case due to young age, a different way of presentation and staging on diagnosis. It has been a quite challenging clinical scenario for the multidisciplinary lung cancer treating team involved in the clinical care. Prognosis remains unpredictable and uncertain despite the best present day evidence-based treatment. Masih, I. Porter, G. Porter, S. Clarke, R. Sidhu, P. Harney, J. McCarthy, A. Convery, R. 2010-11-29 doi:10.1136/bcr.08.2010.3252 Primary adenoid cystic carcinoma of the bronchus in a female teenager BMJ Publishing Group Ltd NOV26_1 2010 82010325 2010-11-29 CASE-REPORT http://casereports.bmj.com/cgi/content/short/2009/may12_1/bcr0820080691?rss=1 Buerger disease (thromboangiitis obliterans) is a non-atherosclerotic segmental inflammatory disease strongly associated with tobacco use, and it affects small and medium-sized blood vessels in the upper and lower extremities. The only known treatment for this disease is complete discontinuation of tobacco use. This report describes the case history of a woman with Buerger disease treated with the oral dual endothelin receptor antagonist bosentan. It is believed that this is the first description in the literature of this use for bosentan. De Haro, J. Florez, A. Fernandez, J. L. Acin, F. 2009-05-12 doi:10.1136/bcr.08.2008.0691 Treatment of Buerger disease (thromboangiitis obliterans) with bosentan: a case report BMJ Publishing Group Ltd MAY12_1 2009 82008069 2009-05-12 CASE-REPORT